{"id":80843,"date":"2026-03-11T13:57:00","date_gmt":"2026-03-11T14:57:00","guid":{"rendered":"https:\/\/cri1149.fr\/?post_type=publication&#038;p=80843"},"modified":"2026-03-11T15:59:48","modified_gmt":"2026-03-11T16:59:48","slug":"imaging-features-of-recently-identified-low-grade-vascular-neoplasia-of-the-liver-hepatic-small-vessel-neoplasm-and-anastomosing-hemangioma","status":"publish","type":"publication","link":"https:\/\/cri1149-dev.mlcom-dev.net\/en\/publication\/imaging-features-of-recently-identified-low-grade-vascular-neoplasia-of-the-liver-hepatic-small-vessel-neoplasm-and-anastomosing-hemangioma\/","title":{"rendered":"Imaging features of recently identified low-grade vascular neoplasia of the liver: hepatic small vessel neoplasm and anastomosing hemangioma"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">Abstract<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Objectives:&nbsp;<\/strong>The aim of this study was to describe the imaging features on dynamic CT and MRI of a series of pathologically confirmed low-grade vascular neoplasia of the liver (LGVNL).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Materials and methods:&nbsp;<\/strong>In this retrospective multicenter study, patients diagnosed with pathologically proven LGVNL between January 2014 and August 2024 and with cross-sectional imaging (CT or MRI) were included. Based on prior studies, we divided the patients into two groups: a group with typical LGVNL features and a group with atypical tumors. Univariable analysis and the logistic regression model were used to evaluate the outcome of typical and atypical LGVNL features.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Results:&nbsp;<\/strong>Twenty-eight patients were included (20 men, mean age 53.7 \u00b1 13.4 [SD] years old). The median size of tumors at diagnosis was 22 mm [IQR, 10-80]. A typical LGVNL pattern including thick continuous peripheral arterial phase &#8220;flower petal shape&#8221; enhancement was found on MRI in 67% (18\/27) with lobulated lesions (p = 0.001), a marked hypersignal on T2-weighted images (p = 0.003) and a high apparent diffusion coefficient (ADC) (mean tumor ADC, 2.1 \u00d7 10<sup>-3<\/sup>&nbsp;\u00b1 0.3 [SD] mm<sup>2<\/sup>\/s) (p = 0.006) with portal and delayed phase filling following contrast administration. An atypical LGVNL pattern was found in 33% (9\/27), including homogeneous arterial phase enhancement that persisted during the portal and delayed phases. After a median follow-up of 16 months, tumor growth was observed in 42% (8\/19) and was faster in patients with the atypical LGVNL pattern (p = 0.013).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Conclusion:&nbsp;<\/strong>The typical imaging pattern of LGVNL that includes arterial phase &#8220;flower petal shape&#8221; enhancement with a marked hypersignal on T2-weighted images and a high ADC was seen in most cases.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Key points:&nbsp;<\/strong>Question Low-grade vascular neoplasia of the liver, including hepatic small vessel neoplasms and anastomosing hemangioma, is a new entity of vascular tumors with few radiological descriptions. Findings Diagnostic imaging criteria include the &#8220;flower petal shape&#8221; enhancement pattern on arterial phase, a marked hypersignal on T2-weighted images and high ADC values. Clinical relevance This multicenter study provides clinical, pathological and imaging data on low-grade vascular neoplasia of the liver and highlights specific imaging features for its diagnosis. Knowledge of these imaging features helps eliminate differential diagnoses.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Keywords:&nbsp;<\/strong>Diagnostic imaging; Liver neoplasms; Magnetic resonance imaging; Vascular neoplasms.<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":true},"category_publication":[],"class_list":["post-80843","publication","type-publication","status-publish","hentry"],"acf":{"numero_de_publication":"Eur Radiol.","date_de_publication":"20260228","numero_doi":"10.1007\/s00330-025-11915-4.","equipe":[335],"auteurs-liste":[{"texte_libre":true,"auteur-lien":null,"auteur-text":"Ma\u00eft\u00e9 Lewin"},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Rauda Aldhaheri"},{"texte_libre":false,"auteur-lien":63210,"auteur-text":""},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Christophe Desterke"},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Anita Paisant"},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Ivan Bricault"},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Paul Borde"},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Gabriel Simon"},{"texte_libre":false,"auteur-lien":71742,"auteur-text":""},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Daniel Cherqui"},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Clara Prud'Homme"},{"texte_libre":false,"auteur-lien":13166,"auteur-text":""},{"texte_libre":true,"auteur-lien":null,"auteur-text":"Astrid Laurent-Bellue"}],"auteurs-manuel":"","liens_externes":[{"url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/40906183\/"}],"liens":null,"paragraphe":"","paragraphe_en":"","documents":null},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Imaging features of recently identified low-grade vascular neoplasia of the liver: hepatic small vessel neoplasm and anastomosing hemangioma - CRI<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Imaging features of recently identified low-grade vascular neoplasia of the liver: hepatic small vessel neoplasm and anastomosing hemangioma - CRI\" \/>\n<meta property=\"og:description\" content=\"Abstract Objectives:&nbsp;The aim of this study was to describe the imaging features on dynamic CT and MRI of a series of pathologically confirmed low-grade vascular neoplasia of the liver (LGVNL). 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